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Researchers identify causal genetic variant linked to common childhood obesity

Researchers identify causal genetic variant linked to common childhood obesity
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

United States , Danielb Burke , Sheridanh Littleton , Diabetes Research , Functional Genomics , Endowed Chair , Cell Genomics ,

Nucleome Therapeutics appoints Dr John Davis as Non-Executive Director of the Board and establishes Scientific Advisory Board of world-leading experts

Nucleome Therapeutics appoints Dr John Davis as Non-Executive Director of the Board and establishes Scientific Advisory Board of world-leading experts
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Rockefeller University , New York , United States , Baden Wüberg , United Kingdom , University Of Pennsylvania , City Of , Useh Jack Bissett , Sonia Quaratino , Pureos Bioventures , Bristol Myers Squibb , Iain Kilty , John Davis , Gerda Blobel , Russell Greig , Jim Hughes , Capella Bioscience , Merck Serono , Sonoma Biotherapeutics , Christopher Miller , Craig Fox , Steve Holmes , Genetic Institute , Genomics Innovation Consulting , Imperial College London , Birmingham University ,

Frontiers | Low mutation rate of spontaneous mutants enables detection of causative genes by comparing whole genome sequences

Frontiers | Low mutation rate of spontaneous mutants enables detection of causative genes by comparing whole genome sequences
frontiersin.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from frontiersin.org Daily Mail and Mail on Sunday newspapers.

Toyama Nougi , Ginbouzu Terada , Honzou Zuhu , Clustal Omega , Aizu Nousho , Ito Shoten , Ricexpro Sato , Pavir Ib , Snpeff Cingolani , Development Program For Agriculture , Technology Research Advancement Institution , Cabinet Office , Moonshot Research , Priority Research , Library Prep Reagent Set Biolabs , Japan Society For The Promotion Of Science , Fukushima University , Kyushu University , Bj Springer International Publishing , Illumina Co Ltd , Scientific Research , Plant Mini Kit , Prep Reagent Set , Illumina Hiseq , Genebank Project , New England Biolabs ,

Substrate specificity mapping of fungal CAZy AA3_2 oxidoreductases | Biotechnology for Biofuels and Bioproducts

Oxidative enzymes targeting lignocellulosic substrates are presently classified into various auxiliary activity (AA) families within the carbohydrate-active enzyme (CAZy) database. Among these, the fungal AA3 glucose–methanol–choline (GMC) oxidoreductases with varying auxiliary activities are attractive sustainable biocatalysts and important for biological function. CAZy AA3 enzymes are further subdivided into four subfamilies, with the large AA3 2 subfamily displaying diverse substrate specificities. However, limited numbers of enzymes in the AA3 2 subfamily are currently biochemically characterized, which limits the homology-based mining of new AA3 2 oxidoreductases. Importantly, novel enzyme activities may be discovered from the uncharacterized parts of this large subfamily. In this study, phylogenetic analyses employing a sequence similarity network (SSN) and maximum likelihood trees were used to cluster AA3 2 sequences. A total of 27 AA3 2 proteins representing differe ....

Aaos Aadhs , Concordia University , Centre For Structural , Functional Genomics ,