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A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.
<p>A research team from the UC Davis Comprehensive Cancer Center has identified a crucial mechanism on a specific cell receptor that can cause cells to self-destruct. Being able to activate the receptor—Fas—and trigger cell death could open the door for improved cancer treatments. Modulating Fas may also extend the benefits of chimeric antigen receptor (CAR) T-cell therapy to solid tumors.</p>