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BBCNEWS BBC News November 6, 2021 18:28:00

A million people without it. they spotted differences in their genes, but interestingly, the differences are similar to those that you might see in someone with anxiety, depression, or insomnia. what that tells us is that these conditions are likely to have a shared genetic origin. they are coming from the same place, effectively, and some of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and ....

A Million , Wasn T , Genetic Variants ,

BBCNEWS BBC News November 6, 2021 16:29:00

The pain, the bloating, i could not go to the supermarket, i could not go to the gym, i could not see friends. when we were allowed go out for social activities, i was not able to go out for dinner. i was not able to go to the office for work. but now, a huge global genetics study has thrown up an interesting clue as to the origins of ibs. scientists from a0 institutions, including a team from here in cambridge, looked at the dna of more than 50,000 people with the condition. then they compared it to the dna of nearly half a million people without it. they spotted differences in their genes, but interestingly, the differences are similar to those that you might see in someone with anxiety, depression, or insomnia. what that tells us is that these conditions are likely to have a shared genetic origin. ....

Global Genetics Study , Origins Of Ibs , A Million ,

BBCNEWS BBC News November 6, 2021 20:23:00

In their genes, but interestingly, the differences are similar to those that you might see in someone with anxiety, depression, or insomnia. what that tells us is that these conditions are likely to have a shared genetic origin. they are coming from the same place, effectively, and some of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and those do work for some people, but not for everybody. ....

Wasn T , Just Ibs , Genetic Variants ,

BBCNEWS BBC News November 6, 2021 19:20:00

The differences are similar to those that you might see in someone with anxiety, depression, or insomnia. what that tells us is that these conditions are likely to have a shared genetic origin. they are coming from the same place, effectively, and some of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and those do work for some people, but not for everybody. so what our study suggests is that ....

Wasn T , Genetic Variants , Neural Processes ,

BBCNEWS BBC News November 6, 2021 17:19:00

Conditions are likely to have a shared genetic origin. they are coming from the same place, effectively, and some of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and those they work for some people, but not for everybody. so what our study suggests is that we need to think about more about treatments that affect the interaction between the brain and the gut. and target some of those nervous ....

Wasn T , Genetic Variants , Neural Processes ,