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BBCNEWS Unspun World with John Simpson June 4, 2024 02:52:00

The human genome project, which was completed 20 years ago, was essentially the sequence of mostly one person. and, of course, we don t have exactly the same dna. of course, the human genome project has been incredibly successful in understanding in general terms, the diseases that are caused by inherited disorders. what we have now is something that s much wider, called the pan genome. but the first genome was taken from, what, an american who was who had african and european ancestry? 70% was taken from an african american that had european and african ancestry, so relatively broad, but it s one person s dna and, of course, there are people from other backgrounds. now, counterintuitively, ....

Human Genome Project , What S Going On , Pan Genome , African American , African Ancestry ,

BBCNEWS Unspun World with John Simpson June 4, 2024 02:51:00

Like me in lebanon i just want to be home. but, for me, the idea of home is lost and i don t know when or whether i will ever be able to go back and live peacefully in my country and contribute to the rebuilding of my own country in a free and democratic way. and that s really what many, many syrians around the world feel that the world has forgotten about their plight. it s 20 years since the human genome was mapped something that offers the hope of cures for a big range of diseases. but the original genome was largely based on the dna of a single individual, an american of african and european descent. now, scientists have mapped what s being called a pan genome, made up of data from 47 people from right across the world. i spoke to pallab ghosh, the bbc science correspondent. ....

Around The World , Human Genome , An American Of African And European Descent , Bbc Monitoring , Pan Genome , Pallab Ghosh ,

BBCNEWS Unspun World with John Simpson June 4, 2024 02:55:00

So many technologies like ai and nuclear physics that also have the potential for terrible harm to humanity, but the point for us as a society is to make sure that they re used for good and, of course, the scientific community have a particular obligation to communicate their sides, to say what it can be used for and what it can t be used for. when you think what the effect of studying the genome of one person was, this is really opening a door to an extraordinary future, isn t it? to find out the instruction manual of how a person is created is an incredible thing, and we ve onlyjust begun to scratch the surface. and now we ve got the pan genome, it s 47 people at the moment. the aim in a few years is for it to be 350 and then even larger as more and more countries get involved. and we re going to get such insights. it s the start of a revolution ....

Nuclear Physics , Instruction Manual , Trouble Isn T , Pan Genome , Of A Revolution ,

BBCNEWS Unspun World with John Simpson June 4, 2024 02:53:00

Even though there s a lot of african dna in the standard genome, it s actually the dna that s most lacking, because there s far more diversity in africa than in any other part of the world, so there are huge differences and what we need more of is different types of dna from africa, as well as from asia and the americas and so forth. so you ve got more variation and something that more accurately represents the different populations of the world. so, the obvious use for that is help with cancer treatments, certain inherited diseases have i got that right? well, it s all genetic research. what will happen is that the medicines may not be as accurate in treating people that have been diagnosed using the standard genome to something that s a bit broader. ....

What S Going On , Cancer Treatments , Genetic Research ,

BBCNEWS Unspun World with John Simpson June 4, 2024 03:52:00

I spoke to pallab ghosh, the bbc science correspondent. the human genome project, which was completed 20 years ago, was essentially the sequence of mostly one person. and, of course, we don t have exactly the same dna. of course, the human genome project has been incredibly successful in understanding in general terms, the diseases that are caused by inherited disorders. what we have now is something that s much wider, called the pan genome. but the first genome was taken from, what, an american who was, who had african and european ancestry? 70% was taken from an african american that had european and african ancestry, so relatively broad, but it s one person s dna, and, of course, there are people from other backgrounds. ....

Bbc Monitoring , Pallab Ghosh , Human Genome Project , What S Going On , Southern Europe , Pan Genome , African American , African Ancestry ,