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Decoding Protein Dance to Halt Inflammation

Decoding Protein Dance to Halt Inflammation
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Erika Pellegrini , Francesco Gervasio , Ella Marushchenko , Pauline Juyoux , Swiss National Supercomputing Centre , Gervasio Lab , University Of Geneva , Matthew Bowler , Swiss National Supercomputing ,

Research opens up new directions to develop drugs for stopping cytokine storms

Constant exposure of cells to stressing agents, such as pathogens, may disturb an organism's normal functioning. To fight stress, cells have developed several coping mechanisms, including the inflammatory response. ....

Erika Pellegrini , Danielle Ellis , Pauline Juyoux , Biologie Structurale , Francesco Gervasio , Swiss National Supercomputing Centre , Protein Data Bank , University Of Geneva , Gervasio Lab , Mitogen Activated Protein Kinase , Protein Data , Nobel Prize , European Synchrotron Radiation Facility , Diamond Light Source , Institut De Biologie Structurale , Covid 19 , Ene Expression , X Ray ,

Switching off cytokine storm

Switching off cytokine storm
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Biologie Structurale , Francesco Gervasio , Pauline Juyoux , Erika Pellegrini , Ella Marushchenko , Isabel Romero Calvo , Protein Data Bank , University Of Geneva , Gervasio Lab , Swiss National Supercomputing Centre , Isabel Romero , Mitogen Activated Protein Kinase , Protein Data , Nobel Prize , European Synchrotron Radiation Facility , Diamond Light Source , Institut De Biologie Structurale ,

Switching off the cytokine storm

In a new paper published in Science, EMBL Grenoble researchers provide essential insights on the molecular activation of the MAP kinase p38α, the final switch triggering the inflammatory response.
Inflammation is a cellular coping mechanism when confronted with stress, such as an infection. However, too much inflammation can damage the functioning of cells and organs. This is the case with cytokine storms, inflammatory cascades that can lead to severe disease and death, recently highlighted during the COVID-19 pandemic.
These results open up new directions to develop drugs to prevent cytokine storms and to study similar processes in two other families of MAP kinases, involved in cancer and Alzheimer’s disease respectively. ....

Francesco Gervasio , Biologie Structurale , Pauline Juyoux , Erika Pellegrini , Gervasio Lab , Swiss National Supercomputing Centre , Protein Data Bank , University Of Geneva , Method Of Research , Mitogen Activated Protein Kinase , Protein Data , Nobel Prize , European Synchrotron Radiation Facility , Diamond Light Source , Institut De Biologie Structurale ,

Switching off the cytokine storm

Switching off the cytokine storm
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Erika Pellegrini , Biologie Structurale , Francesco Gervasio , Pauline Juyoux , Gervasio Lab , Swiss National Supercomputing Centre , Protein Data Bank , University Of Geneva , Mitogen Activated Protein Kinase , Protein Data , Nobel Prize , European Synchrotron Radiation Facility , Diamond Light Source , Institut De Biologie Structurale ,