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CU Cancer Center researchers receive PRCRP grant to investigate metastasis Two members of the University of Colorado Cancer Center have received prestigious Idea Awards from the U.S. Department of Defense's Peer Reviewed Cancer Research Program (PRCRP). Founded in 2009, the PRCRP funds cancer research to support service members, their families, and the American public. Since members of the military are exposed to hazardous environments due to the nature of their service and are at risk for the development of many types of cancers, the PRCRP's mission is to promote high-impact research for can...

Breast cancer is harmful enough on its own, but when cancer cells start to metastasize -- or spread into the body from their original location -- the disease becomes even more fatal and difficult to treat.

The transformation Ford and her team are studying happens when cells called epithelial cells, which are more adherent to one another and less likely to spread to other parts of the body, start to take on the characteristics of mesenchymal cells, which are more migratory and more likely to invade other parts of the body. This transformation is referred to as the epithelial-to-mesenchymal transition.