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Mutant Gene-Targeted Immunotherapy Approach Developed - Vimarsana News

Mutant Gene-Targeted Immunotherapy Approach Developed

share: This news release, issued by Johns Hopkins Medicine, describes a novel targeted immunotherapy approach. This new approach employs bispecific antibodies to treat cancer by eliciting a Tcell response against mutated p53. The researchers used the Highly Automated Macromolecular Crystallography (AMX) and Frontier Microfocusing Macromolecular Crystallography (FMX) beamlines to characterize the molecular structure of the proteins. AMX and FMX are beamlines at the National Synchrotron Light Source II (NSLS-II)—a U.S. Department of Energy (DOE) Office of Science User Facility at Broo...

Source: bnl.gov
Wounded Warrior Project Outlines the Challenges Facing Veterans Exposed to Toxins - Vimarsana News

Wounded Warrior Project Outlines the Challenges Facing Veterans Exposed to Toxins

Wounded Warrior Project Outlines the Challenges Facing Veterans Exposed to Toxins News provided by Share this article WASHINGTON, March 11, 2021 /PRNewswire/ -- Wounded Warrior Project ® (WWP) testified yesterday before the Senate Committee on Veterans' Affairs on the lasting effects toxic exposures have on veterans. WWP also shared information on the support it provides to the many veterans who were exposed during military service. Wounded Warrior Project (WWP) testified yesterday before the Senate Committee on Veterans’ Affairs on the lasting effects toxic exposures have on veterans. WW...

Mutant gene-targeted immunotherapy approach developed - Vimarsana News

Mutant gene-targeted immunotherapy approach developed

Two of the three research studies -- led by Jacqueline Douglass, M.D., Ph.D. candidate at the Johns Hopkins University School of Medicine and Emily Han-Chung Hsiue, M.D., Ph.D., postdoctoral fellow at Johns Hopkins--report on a precision medicine immunotherapy approach that specifically kills cancer cells by targeting mutant protein fragments presented as antigens on the cancer cell surface. Although common across cancer types, p53 mutations have not been successfully targeted with drugs. Genetic alterations in tumor suppressor genes often resulted in their functional inactivation. "Tradition...

N.H. Launches New Effort to Help Homebound Residents Get Vaccinated - Vimarsana News

N.H. Launches New Effort to Help Homebound Residents Get Vaccinated

Starting next week, New Hampshire will begin a large-scale effort to get more vaccines to people who are unable to get to fixed vaccine clinics — either

Source: nhpr.org