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Biosensors to Measure Antibiotics in Mammals Developed

Biosensors to Measure Antibiotics in Mammals Developed
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Alex Smith , Wilfried Weber , Patrick Seeger , University Of Freiburg , Freiburg Center , Centre For Integrative Biological Signalling , Develop Biosensors , Measure Antibiotics , Can Dincer , Interactive Materials , Bioinspired Technologies , Synthetic Biology , Integrative Biological Signalling , Advanced Materials , Ceren Ates , Integrative Biological Signalling Studies , அலெக்ஸ் ஸ்மித் , பேட்ரிக் பார்ப்பவர் , ஊடாடும் பொருட்கள் , செயற்கை உயிரியல் ,

A remote control for gene transfer

A remote control for gene transfer
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Wolfgang Schamel , Wilfried Weber , Michal Roessler , University Of Freiburg , Centre For Integrative Biological Signalling , Integrative Biological Signalling Studies , Integrative Biological Signalling , ஓநாய் ஸ்கேமல் , மைக்கேல் ரோஸ்லர் ,

How Plants Find Their Symbiotic Partners

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How Plants Find Their Symbiotic Partners
A root hair (blue) grows around the symbiotic bacteria (red). Photo: Pengbo Liang/University of Freiburg
What would it be like to produce fertilizer in your own basement? Leguminous plants, like peas, beans, and various species of clover, obtain the organic nitrogen they need for their growth from symbiotic soil bacteria via specialized structures in their roots. A team led by the cell biologist Prof. Dr. Thomas Ott from the University of Freiburg’s Faculty of Biology has now detected a factor in the root cells that the plants need for the initial contact with these so-called root-associated bacteria, which live in the soil. They discovered a protein found only in legumes called symbiotic formin 1 (SYFO1) and demonstrated the essential role it plays in symbiosis. Together with the molecular biologist Prof. Dr. Robert Grosse University of Freiburg’s Faculty ....

Thomas Ott , Pierre Marc Delaux , University Of Freiburg Faculty Biology , Pengbo Liang University Of Freiburg , Laboratoire De Recherche En Sciences , Centre For Integrative Biological Signalling , How Plants Find Their Symbiotic , Robert Grosse University , Laboratoire De Recherche , Integrative Biological Signalling , தாமஸ் ஆட் , ஆய்வக டி ரெக்ஃப்‌ச் ,

Anti-cancer drug's mode of operation deciphered

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IMAGE: Freiburg researchers investigate how the membrane protein CD20 organizes the nanostructures on the B cell membrane.
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Credit: Illustration: Julia Jullesova
Rituximab, an anti-cancer drug targeting the membrane protein CD20, was the first approved therapeutic antibody against B tumor cells. Immunologists at the University of Freiburg have now solved a mystery about how it works. A team headed by Professor Dr. Michael Reth used cell cultures, healthy cells, and cells from cancer patients to investigate how CD20 organizes the nanostructures on the B cell membrane. If the protein is missing or Rituximab binds to it, the organization of the B cell surface changes. The resting B cell is activated in the process. The team has published the research in the journal ....

Michael Reth , University Of Freiburg , Institute Of Biology , Centre For Biological Signalling Studies He , National Academy Of Science , Centre For Integrative Biological Signalling , National Academy , Molecular Immunology , Integrative Biological Signalling , Cell Biology , Medicine Health , மைக்கேல் ரெத் , நிறுவனம் ஆஃப் உயிரியல் , தேசிய கலைக்கழகம் ஆஃப் அறிவியல் , தேசிய கலைக்கழகம் , மூலக்கூறு நோயெதிர்ப்பு , செல் உயிரியல் , மருந்து ஆரோக்கியம் ,

Turbo boosters for the immune system

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With the Proof of Concept funding line, the ERC grants recipients of ERC frontier research funds (Starting, Consolidator, Advanced or Synergy grants) with 150.000 Euro to develop promising ideas with commercial or societal potential to the proof of concept stage. With this funding, Olaf Groß and his team in the Metabolism and Inflammation Group at the Institute of Neuropathology of the Medical Center - University of Freiburg will test whether a new class of immune activating drugs they discovered can boost the effectiveness of cancer immunotherapies or vaccines against infectious diseases.
Groß studies a protein complex called the inflammasome within macrophages, specialized cells of the body s defense system that patrol tissues for signs of danger. When their inflammasome is activated, macrophages sound the alarm by releasing of potent factors called cytokines. These cytokines alert other cells in the body, initiating an inflammatory response that helps other ....

Technical University Of Munich , University Of Freiburg , Institute Of Neuropathology The Medical Center , University Of Lausanne , Centre For Integrative Biological Signalling , Inflammation Group , Olaf Gro , Medical Center , Technical University , University Medical , Emerging Field , Metabolism Research , Integrative Biological Signalling , Medicine Health , தொழில்நுட்ப பல்கலைக்கழகம் ஆஃப் முனிச் , ஓலேஃப் க்ரோ , மருத்துவ மையம் , தொழில்நுட்ப பல்கலைக்கழகம் , பல்கலைக்கழகம் மருத்துவ , வளர்ந்து வருகிறது புலம் , வளர்சிதை மாற்றம் ஆராய்ச்சி , மருந்து ஆரோக்கியம் ,