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Drugs manufactured in puerto rico and it says the saline shortage will improve in a couple weeks. we talked to one clinic in california that said it has enough sailing to get to february and after that it will have to reassess. >> bret: thank you. the republican accidents in congress continues tonight. california congressman darrell isis says he will -- darell iss issa. mike emanuel what's shaping up to be mayhem. >> i came to congress for four years and i have stayed for 18. >> california republican darrell i saw rejected the suggestion his district could go to a democrat. >> the economy says...

>> bret: big names on the republican side, especially in the house, saying they are running again. three senators, republicans, not seeking reelection. corker, flake, hatch. 43 house members retiring or running for higher office or another office in 2018. 29 republicans, 14 democrats. you take a look at the balance of power and democrats need just 24 seats to take back the house. big names, a.b. issa, royce. >> there are many reasons it's an individual decision for people who decide they have stayed too long or they are in a stage in life where they want to do other things but this year is the...

Assuming the republicans are going to lose control. >> bret: you mention the comparison. seats, gains, lost. some states like california, state and local tax issue and tax laws factoring in for republicans. >> it's also just moving left. california provided the entire margin of popular vote victory for hillary clinton. in this last election. this is really bad news for republicans. a lot of republican strategists thought issa was a goner anyway. he barely won. popularity going down. they were really surprised by ed royce. they expected him to win his seat. they didn't get any warning of it. th...

Fired up. what do you make of that? >> andrea: it's funny. i said you don't make a very good witness. he also doesn't make a very good lawyer. i thought pressuring was good. this is such a complex story. i think a lot of us are wondering why are we still talking about this? is this deja vu? holder has been brought to the hill a number of times. the reason we're still talk about this, they have not answered the question. by "they" i mean eric holder. did it come to him? did he approved? who approved at the department of justice the guns to cross the border? that is the question. what did he kno...

Fired up. what do you make of that? >> andrea: it's funny. i said you don't make a very good witness. he also doesn't make a very good lawyer. i thought pressuring was good. this is such a complex story. i think a lot of us are wondering why are we still talking about this? is this deja vu? holder has been brought to the hill a number of times. the reason we're still talk about this, they have not answered the question. by "they" i mean eric holder. did it come to him? did he approved? who approved at the department of justice the guns to cross the border? that is the question. what did he kno...