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fierce street fighting in eastern ukraine. president zelensky says his forces are "holding on", but warns troops are running low on ammunition. and queen elizabeth ii becomes the world's second longest serving monarch — only louis xiv of france has ruled for longer. good afternoon. if you have just joined if you havejustjoined us, welcome to bbc news. a leading business group has told the bbc that households have been cutting back on spending because of the cost of living crisis, and will go into their own recession this year. tony danker, the director general of the confederation ...

Designing new medicines is like playing with a jigsaw, the shape of the drug needs to fit the shape of the illness in your body, so it is a lot easier to find a match if you can see what they both look like in 3d. it's so real. pharmaceuticalstudent, may, here... hello, may. ..had the idea of students using virtual reality, after she went on an industry placement. so, this is a protein that is linked to blood clots, yeah, so things like strokes... yes, this is thrombin, and this is the molecule in our body that's responsible for causing blood clots, so, as you can see, the protein is quite a c...