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Researchers have identified a molecular mechanism that helps regulate the progression of castration-resistant prostate cancer (CRPC). Downregulation of the protein FOXA1 regulates hypoxia, or lack of oxygen, to promote prostate cancer progression.<br /><br />
A transcription factor associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis.
A transcription factor normally associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis, according to a Northwestern Medicine study published in Nature Genetics.