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Born in Calcutta, India , he attended boarding school in England before reading PPE at Oxford. Dr Mosley tried his hand working as an investment banker before retraining as a doctor.
Police fear Dr Mosley, 67, may have 'slipped, tripped or fallen' while hiking alone in blistering 36C (97F) heat on Wednesday.
Police and firefighters are using drones to scour the island.
Michael Mosley, a prolific presenter of science and lifestyle shows, has gone missing on the Greek island of Symi.
The TV doctor and columnist, known for his appearances on The One Show and This Morning, vanished on Wednesday.