Partnership aims to accelerate gene therapies for rare diseases
It will focus on projects that illuminate the basic biology of the adeno-associated virus, one of the most common gene-delivery vectors.
Source: statnews.com
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Pandemic Research Lays Path Forward for Study of Rare Diseases
NIH experts: Rapid response to COVID-19 has 'silver lining' for tough-to-treat diseases
Source: medpagetoday.com
Four-part small-molecule cocktail can prevent cellular stress
Four-part small-molecule cocktail can prevent cellular stress Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function. The researchers suggest that the cocktail could enhance the potential therapeutic uses of stem cells, ranging from treating diseases and conditions -- such as diabetes, Parkinson's disease and spinal cord injury -- to genome editing. Human pluripotent stem cells are cells that, in theory, can...
Source: news-medical.net
Scientists identify small-molecule cocktail to improve stem cell use in research and disease treatments
Chen et al., Nature Methods Researchers at the National Institutes of Health have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function. The researchers suggest that the cocktail could enhance the potential therapeutic uses of stem cells, ranging from treating diseases and conditions — such as diabetes, Parkinson’s disease and spinal cord injury — to genome editing. Human pluripotent stem cells are cells that, in theory, can grow forever and serve as an inexha...
Source: nih.gov
Scientists find small molecule cocktail to improve stem cell use in research, medicine
E-Mail Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function. The researchers suggest that the cocktail could enhance the potential therapeutic uses of stem cells, ranging from treating diseases and conditions -- such as diabetes, Parkinson's disease and spinal cord injury -- to genome editing. Human pluripotent stem cells are cells that, in theory, can grow forever and serve as an inexhaustible source fo...
Source: eurekalert.org