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Lab-cultured mouse embryos, grown for an extended period, offer a new window on fetal development In the course of an experiment pushing the length limits of in vitro growth, mouse embryos went from translucent clumps of cells to fetuses with beating hearts and blood cells. Image credit: Jacob Hanna In a potential methods breakthrough, stem cell biologists grew mouse embryos for five-and-a-half days in vitro, longer than ever before. Appearing recently in Nature, the study unveils new protocols and equipment, including a temperature-and-pressure-controlled incubator that enabled the coauthor...

Jun Wu's team at the University of Texas Southwestern Medical Center in Dallas have created hollow balls of cells that closely resemble embryos at the stage when they usually implant in the womb — known as blastocysts. The new laboratory-made embryo-like entities have been dubbed "blastoids." UT Southwestern Medical Center toggle caption UT Southwestern Medical Center Jun Wu's team at the University of Texas Southwestern Medical Center in Dallas have created hollow balls of cells that closely resemble embryos at the stage when they usually implant...

Scientists have created a model of an early human embryo from skin cells, a discovery which they say will revolutionise research into the causes of early miscarriage, infertility and early human development. Researchers have successfully reprogrammed these fibroblasts or skin cells into a 3D cellular structure that is similar to human blastocysts. Called iBlastoids, these can be used to model the biology of early human embryos in the laboratory, according to a new study. Scientists say this is a significant breakthrough for the future study of early human development and infertility. A few da...

Listen • 4:01 Dr. Jun Wu's team at University of Texas Southwestern medical Center at Dallas have created hollow balls of cells that closely resemble embryos at the stage when they usually implant in the womb, which are known as blastocysts. The new laboratory-made embryos have been dubbed "blastoids." These structures made from living human cells are similar to human embryos at the stage when they implant in the womb. They allow scientists to research new ways to treat infertility. For decades, science has been trying to unlock the mysteries of how a single cell becomes...

Researchers have successfully grown model versions of early human embryos by “reprogramming” cells from human skin. The breakthrough potentially opens up new ways to study the earliest phases of human development, learn more about developmental disorders, infertility and genetic diseases, and perhaps even improve the success of IVF treatment. In a study published in Nature today, a team led by our colleague Jose Polo discovered that when skin cells are treated in a particular way, 3D structures similar to early human embryos form. A US-Chinese research group led by Jun Wu also reported a...