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The report from the trenches of the first day of the 10th Aging Research for Drug Discovery, Copenhagen, August 29, 2023

Katrin Andreasson discusses how immune cells can cause harmful brain inflammation and contribute to the development of neurodegenerative diseases like Alzheimer’s disease.

'Exciting treatment that could sharpen minds and gives hope to people with Alzheimer's' Mirror 6 days ago Miriam Stoppard Medical research often creeps forward slowly. Advances emerge from painstaking ­investigation starting with basic lab studies, then in animals, first in small animals such as mice, moving on to larger animals before being tried in human beings. Now from this typical march of progress comes an exciting treatment that, on the face of it, keeps the mind and memory sharp well into old age. It’s a very early study where an anti-inflammatory drug successfull...

Study reveals immune driver of brain aging Suppose Smokey Bear were to lose it and start setting forest fires instead of putting them out. That roughly describes the behavior of certain cells of our immune system that become increasingly irascible as we grow older. Instead of stamping out embers, they stoke the flames of chronic inflammation. Biologists have long theorized that reducing this inflammation could slow the aging process and delay the onset of age-associated conditions, such as heart disease, Alzheimer’s disease, cancer and frailty, and perhaps even forestall the gradual loss of...

Exciting Study on Mouse Immune Cells Reveals How We Might Reverse Cognitive Decline SARA HUSSEIN, AFP 23 JANUARY 2021 The march of time can be unkind to the human body, but new research hints at a cause – and possible solution – for some of the ailments and decline that often come with age.   Scientists have long known that cognitive decline as we get older and specific age-related diseases including Alzheimer's are linked to inflammation, but they are still uncovering precisely why and how this is the case. Research published Wednesday in the journal Naturepinpoints the role of a m...