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/PRNewswire/ -- Researchers affiliated with Kawasaki INnovation Gateway at SKYFRONT (KING SKYFRONT) and their collaborators report on antibody delivery...

/PRNewswire/ -- Researchers affiliated with Kawasaki INnovation Gateway at SKYFRONT (KING SKYFRONT) and their collaborators report on antibody delivery...

Improving intellectual property creation and management in R&D A case study of a Japanese funding program leads to suggestions for optimizing scientific and technological innovation Generating and managing intellectual property is an important aspect of research and development (R&D), traditionally carried out in industrial laboratories. At the same time, innovation is often achieved through collaboration between academia, industry and government. Optimal intellectual property management is then far from straightforward because of the different actors involved, all having different specialtie...

It is known that c-Myc is involved in cancer cell proliferation and angiogenesis and changes the cell cycle, suppresses normal cell differentiation, and promotes cancer metastasis. It is a typical proto-oncogene that regulates many genes related to growth factors and is known to be involved in developing of many cancers, such as chromosomal translocation in Burkitt lymphoma. Therefore, drug discovery research is being conducted worldwide as an anticancer drug targeting this transcription factor that can directly attack cancer stem cells. However, since embryonic lethality occurs in c-Myc knoc...

Loading video... VIDEO: Nanomedicines consisting of one molecule of oligonucleotide and one or two molecules of Y-shaped block copolymer(s), of which the size is approximately 18 nm and is in dynamic equilibrium with free Y-shaped... view more  Credit: 2021 Innovation Center of NanoMedicine Summary Ultra-small nanomedicines of approximately 18 nm were fabricated by dynamic ion-pairing between Y-shaped block copolymers and nucleic acid drugs, such as siRNA and antisense drugs. Chemically modified and double-stranded oligonucleotides dramatically enhanced the stability of the ultra-smal...