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Two VASCI Faculty Receive Major NIH Grants from its Knockout Mouse Project


December 21, 2020
Jesse Mager
UMass Amherst veterinary and animal science researchers Kim Tremblay and Jesse Mager, a wife-and-husband team nationally known for expertise in embryonic development, have each received five-year awards from the National Institutes of Health (NIH) to study distinct stages of embryo development in mice that have had essential genes knocked out. They will collaborate with Wei Cui, director of the Animal Models Core at the campus’s Institute for Applied Life Sciences.
Specifically, Mager and Tremblay, who are co-investigators on each other’s grants, have chosen to investigate a large number of lethal genes whose function is not well understood or not studied at all. These knock-out animals are produced by the Knockout Mouse Project (KOMP), part of the international mouse phenotyping consortium (IMPC), a global effort to identify the function of every protein-coding gene in the mouse genome. The genes that Mager and Tremblay study are thos ....

Jesse Mager , Wei Cui , Kim Tremblay , National Institutes Of Health , Institute For Applied Life Sciences , National Institutes , Animal Models Core , Applied Life , Knockout Mouse Project , ஜெஸ்ஸி மாகேர் , வெய் சுத்தி , கிம் நடுக்கம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , நிறுவனம் க்கு பயன்படுத்தப்பட்டது வாழ்க்கை அறிவியல் , தேசிய நிறுவனங்கள் , விலங்கு மாதிரிகள் கோர் , பயன்படுத்தப்பட்டது வாழ்க்கை , நாக் அவுட் சுட்டி ப்ராஜெக்ட் ,