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This was at a time when vaccines were in short supply and preliminary research suggested that widening the gap from the manufacturer-recommended four weeks to 12 increased the immune response. But in May the guidance was changed to eight weeks as cases associated with the Delta variant continued to rise in the UK. Prof Susanna Duanchie, of the University of Oxford, who is the joint chief investigator in the study, known as Pitch, said: “The original recommendation from JCVI was 12 weeks and this was based on a lot of knowledge from other vaccines that often having a longer interval [betw...

Eight-weeks between first and second Pfizer vaccine doses the 'sweet spot’ for fighting Delta variant 'The decision to put it to eight weeks is really balancing all the wider issues, the pros and cons' The video will auto-play soon8Cancel Play now Sign up to the Grimsby Live newsletter for daily updates and breaking newsInvalid EmailSomething went wrong, please try again later. Sign up here! We use your sign-up to provide content in ways you've consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubs...

An eight-week gap between the first and second doses of the Pfizer/BioNTech Covid-19 vaccine is a “sweet spot” when it comes to generating strong immune response while protecting the UK population against the Delta variant of coronavirus, scientists have said. In a new study, funded by the Department of Health and Social Care (DHSC), researchers have found that when compared to a four-week gap, a 10-week interval between the doses produces higher antibody levels, as well as a higher proportion of a group of infection-fighting cells in the body known as “helper” T cells. At the start o...