"The importance of elastin and its role in auricular cartilage tissue e" by Steven Posniak, Johnson H.Y. Chung et al.
Cartilage regeneration remains a challenge in the field of regenerative medicine. Advances in cartilage regeneration would greatly benefit patients requiring reconstructive surgeries as a result of injury or congenital deformities. Injury can be of the form of trauma or congenital deformities such as microtia, where afflicted children are born with a deformed ear and consequently often experience self-confidence and other psychological issues. Prevalence rates vary among regions but may be as high as 17.4 per 10,000 births. Current treatments for people with this condition are inadequate, with...