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Researchers map brain cell changes in Alzheimer's disease | MIT News | Massachusetts Institute of Technology

A study by scientists at MIT and at the Broad Institute of MIT and Harvard shows how brain cells located near amyloid plaques and tau tangles change as Alzheimer’s disease progresses. The technique, called STARmap PLUS, is the first to simultaneously map gene expression of individual cells and their location, as well as the spatial distribution of specific proteins in intact tissue samples. ....

Morgan Sheng , Zhaowen Zhou , Xiao Wang , Jiahao Huang , Broad Institute , Psychiatric Research , Searle Scholars Foundation , Merkin Institute , Stanley Center , Nature Neuroscience , Merkin Fellow , Biao Wang , Broad Institute , Lzheimers Map ,