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Blogs | | A treosulfan-based reduced-toxicity conditioning regimen has significantly improved hematopoietic cell transplantation outcomes for patients with high-risk thalassemia major and hematologic malignancies.However, complications related to regimen-related toxicities, mixed chimerism and graft rejection limit its success.
Treatment intensification with darolutamide plus androgen deprivation therapy and docetaxel improved OS among men with metastatic hormone-sensitive prostate cancer regardless of disease volume or risk, according to study results.The benefits of early treatment intensification appeared consistent among men with high-volume or low-volume disease, as well as those with high-risk or low-risk disease,
Perichemotherapy antibiotics appeared associated with longer survival among patients with metastatic pancreatic ductal adenocarcinoma treated with gemcitabine, according to retrospective study results.Researchers did not observe the same benefit among patients treated with fluorouracil.
An oncology financial navigation intervention decreased financial toxicity among patients with blood cancers and their caregivers, according to study results.The intervention — called Coverage and Cost-of-Care Links (CC Links) — also received high ratings for acceptability and appropriateness, findings showed.
A high percentage of people with cancer exhibit what are known as SPPADE symptoms, according to study results.Investigators interviewed 31,886 people with cancer and assessed them for these symptoms, which include sleep disturbance, pain, physical function impairment, anxiety, depression, and low energy or fatigue.