Page 2 - Mark Tuszynski News Today : Breaking News, Live Updates & Top Stories | Vimarsana

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease UC San Diego researchers will inject harmless virus carrying a restorative gene into participants’ brains, where earlier animal studies suggest it may slow, prevent or reverse progression of the neurological disorder February 18, 2021  |  Scott LaFee News_release Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer...

By Rebekah Gonzalez Feb 23, 2021 The University of San Diego School of Medicine has launched a first-in-human Phase I clinical trial to test the benefits and safety of gene therapy. They are now looking for participants. Researchers are using the trial to see if gene therapy can be used to deliver a key protein (brain-derived neurotrophic factor or BDNF) into the brains of those with Alzheimer's disease or Mild Cognitive Impairment, which often leads to dementia. "We found that delivering BDNF to the part of the brain that is affected earliest in Alzheimer's disease - the entorhinal cortex...

The Phase 1 clinical trial involves a type of gene therapy that will be used for the first time in humans