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Mast cell activation may underlie inflammation in severe COVID-19 - Vimarsana News

Mast cell activation may underlie inflammation in severe COVID-19

A new preprint research paper posted to the medRxiv* server points to mast cells as major culprits in the etiology of severe and critical COVID-19. This could suggest suitable therapeutic and preventive interventions to reduce the morbidity and mortality of this viral illness.

People with venom allergies are more likely to have bone marrow disorder - Vimarsana News

People with venom allergies are more likely to have bone marrow disorder

People with venom allergies are more likely to have bone marrow disorder Researchers at Michigan Medicine found that people with venom allergies are much more likely to suffer mastocytosis, a bone marrow disorder that causes higher risk of fatal reactions. The team of allergists examined approximately 27 million United States patients through an insurance database - easily becoming the nation's largest study of allergies to bee and wasp stings, or hymenoptera venom. The results, published in the Journal of Allergy and Clinical Immunology, revealed mastocytosis in fewer than 0.1% of venom all...

'Cells at Work' 2nd Anime Season Reveals Final DVD/BD Release Artwork - Vimarsana News

'Cells at Work' 2nd Anime Season Reveals Final DVD/BD Release Artwork

© Akane Shimizu / Kodansha / Aniplex / David Production The winter 2021 anime series Cells at Work is getting its home video release handled by Aniplex Japan and they’ve set their standard style release for it. The eight-episode series is getting a four-volume release that began on February 3rd, 2021. With the third set coming up on April 7th, 2021, we now have the cover artwork for it. The discs are priced between 4,000 yen to 6,800 yen on Blu-ray as the episode count per disc is set at 1/2/3/2. The DVDs are priced 1,000 yen cheaper overall. The feature film is scheduled for a March 24th...

AB Science announces that a new independent publication confirms the role of masitinib as a potential therapy in neurodegenerative disorders including Alzheimer's Disease - Vimarsana News

AB Science announces that a new independent publication confirms the role of masitinib as a potential therapy in neurodegenerative disorders including Alzheimer's Disease

in vitro and in vivo (APPswe/PS1dE9 mouse model of Alzheimer’s disease) experiments that show increased mast cell hemichannel activity after treatment with amyloid peptide (Ab 25–35), with subsequent degranulation response and enhanced histamine release [2]. The number of mast cells in hippocampal and cortical areas increased drastically even before amyloid plaque deposits became evident, suggesting that mast cells are one of the first brain cells to recognize and respond to amyloid peptides, and thus may play a critical role in the onset and progression of Alzheimer’s disease. Treatme...

'Cells at Work' 2nd Anime Season Previews 8th & Final Episode - Vimarsana News

'Cells at Work' 2nd Anime Season Previews 8th & Final Episode

© Akane Shimizu / Kodansha / Aniplex / David Production The winter 2021 anime series Cells at Work is getting some new attention as the official site is debuting some new promotional material. With the season underway, the eighth and final episode of the series is due out on February 27th, 2021 and now the first commercial spot preview for it has arrived below! The promos are done via Twitter as the YouTube versions are region-locked to Japan. The series was directed by Kenichi Suzuki based on the series composition by Yuuko Kakihara. Takahiko Yoshida handled the character design and served...