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An atomic switch is bringing us closer to highly effective solid-state batteries for electric vehicles.

Product News: ZEISS introduces new lattice light sheet fluorescence microscope 30 Dec 2020 With the release of ZEISS Lattice Lightsheet 7, ZEISS places a turn-key lattice light sheet instrument at the disposal of the life science research community. Based on the pioneering research and developments of Ernst H. K. Stelzer while at EMBL, Heidelberg, on light sheet technology and of Nobel laureate Eric Betzig while at the Janelia Research Campus of HHMI on structuring light sheets as optical lattices to render them thinner and longer, ZEISS Lattice Lightsheet 7 is tailored to observing cellular ...

Loading video... VIDEO: The ABCB1 protein squeezes fat-soluble compounds out of the cell through a major twist in the protein structure. view more  Credit: Kyoto University iCeMS In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS), discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment. How it did this has remained a mystery for the past 35 years. Now, his team has published a review in the journal FEBS Letters, summar...

 E-Mail IMAGE: Abnormalities in the cholesterol transport protein ABCA13 have been shown to lead to schizophrenia in a mouse model. view more  Credit: Mindy Takamiya/Kyoto University iCeMS Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens. Now, Kazumitsu Ueda of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan have provided evidence that mice with disrupted ABCA13 protein demonstrate a hall...

Protein employs twist‐and‐squeeze mechanism to expel chemotherapeutics from cancer cells In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS), discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment. How it did this has remained a mystery for the past 35 years. Now, his team has published a review in the journal FEBS Letters, summarizing what they have learned following years of research on this and other ATP-binding casset...