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Transcripts for BBCNEWS Newsday 20240604 00:13:00

It s being described as momentous a major trial of an experimental dementia drug has shown for the first time that the progression of early stage alzheimer s can be slowed down. the effects of the treatment were small, but have prompted huge excitement among researchers. our medical editor, fergus walsh, reports. dementia is the most feared condition among older people, but mavis, who is 88, is enjoying her retirement, such as coffee mornings, despite a diagnosis of early stage alzheimer s. i don t feel old, i don t feel tired particularly. we enjoy life together, and i ve got family which i absolutely adore and enjoy them. life, i think, is rather nice. mavis short term memory is badly affected, and she increasingly relies on her husband, rodney. what are you going to do with yourself today? ....

Brain By Alzheimer S , Dementia Drug , Fergus Walsh , Coffee Mornings , Short Term Memory ,

Transcripts for BBCNEWS Newsday 20240604 00:15:00

Or not widely available. but there will be a clamour for the treatment, which in the trial slowed cognitive decline by about a quarter over 18 months. lecanemab is not a cure. it can only help patients in the early stages of alzheimer s, but it is the first drug to convincingly slow cognitive decline, so that makes it a breakthrough against this relentless disease. doctors running the trial are delighted by the findings. this is so exciting because now we are getting results, the first results, that are indicating that the drug is successfully treating the underlying cause and it is slowing down the symptoms of cognitive impairment, and also the behavioural symptoms associated with alzheimer s disease. you look nice and warm. mavis may have been on a dummy or placebo drug during the trial, ....

Brain By Alzheimer S , Cognitive Impairment ,

Transcripts for BBCNEWS Newsday 20240604 00:16:00

But is now definitely getting lecanemab. she receives an infusion every two weeks at this clinic in surrey. now, i heard you had a big . coffee morning this morning. oh, did i? her alzheimer s is still progressing, but her husband says it s not robbed her of her personality. we don t want to just sit around and wait for the inevitable, which is why we applied for the trial, and we are now extremely pleased that we did so, because, you know, it appears to have had a very positive effect on mavis. mavis had no side effects, but others on the trial did, including brain swelling and microbleeds. lecanemab is farfrom being a perfect drug, but alzheimer s researchers say it points the way to better treatments in future. ....

Brain By Alzheimer S , Side Effects , Brain Swelling ,

Transcripts for CNN Diana 20240604 01:09:00

Massive. massive really only for one person, mavis for diana. here they are, barely two years in, and diana is becoming this global icon, and that really starts to put a strain on their marriage. it was a changing sense of where the power and the love was, and that was going to stay like tha t forever. ....

Diana Didn T , Tha T Forever ,