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Bordeaux-Begles dominated Castres to win 23-10 on Saturday and increase their lead at the top of the French Top 14 table, while reigning champions Toulouse lost at home to Racing 92.
La Rochelle have now lost three of their last four games.
There were wins for Leicester Tigers and Racing 92 over Connacht and Ospreys in the Champions Cup games in Ireland and Wales on Saturday.
Racing 92 overwhelmed Northampton 45-14 on Friday in the opening match of the European Rugby Cup season.
Racing 92 overwhelmed Northampton 45-14 on Friday in the opening match of the European Rugby Cup season.