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Aims: This study examined the origins and evolution of the AdeABC, AdeFGH and AdeIJK efflux pumps in the Acinetobacter genus, including human and animal pathogens and species from non-clinical environments. Methods: Comparative genome analyses were performed using the reference sequences for 70 Acinetobacter species to identify putative orthologs of AdeABC, AdeFGH and AdeIJK and their regulators. Sequence similarities and the genomic locations of coding sequences were correlated with phylogeny to infer modes of evolution. Intraspecies variation was assessed in species of interest using up to 2...

A team of scientists from The Hormel Institute, University of Minnesota, have published research that could have implications for the development of Alzheimer’s disease.

'This research would not be possible without the advances in cryo-EM, which The Hormel Institute was an early leader in recognizing and adopting.'

'This grant will provide a pathway to bridge basic and clinical research and open up new directions in working with scientists...'