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Study reveals seasonal MERS-CoV peaks in Kenyan camels and potential human transmission

Researchers found biphasic peaks of MERS-CoV in dromedaries in Kenya, with evidence of serologic exposure among slaughterhouse workers, highlighting potential human transmission risks.

Kenya , Ethiopia , Laisamis , Eastern , Isiolo , Akaki , Adis-abeba , Kenyan , Emerging-infectious-diseases , Middle-east , Cov-incidence

WHO identities first case MERS-CoV in UAE this year

The case pertains to a 28-year-old male from UAE with no travel history.

Abu-dhabi , Middle-east , Member-states , Mers-cov , Uae , Camels ,

Man Tests Positive For MERS-Coronavirus In Abu Dhabi Near Oman Border: WHO

A 28-year-old man has tested positive for the potentially fatal Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in a city in Abu Dhabi on the border with Oman, the World Health Organization said on Monday.

Oman , Abu-dhabi , World-health-organization , Man-tests-positive-for , Coronavirus-in-abu-dhabi , Middle-east-respiratory-syndrome-coronavirus , United-arab-emirate , United-nations-climate-change-conference , Mers-cov , World-health-organisation-who- ,

WHO cautions against MERS-CoV, calls for strong surveillance

The World Health Organization (WHO) has cautioned against the sporadic case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and re-emphasised strong surveillance for...

Dhahirah , Az-zahirah , Oman , Sultanate-of-oman , World-health-organization , Middle-east-respiratory-syndrome-coronavirus , Who , Cautions , Against , Mers-cov , Calls

The 'NeoCoV' Virus: Should You Be Concerned?

For several days now, online people have been busy looking up a potential new virus that has been flagged by a number of publications in China and India

Wuhan , Hubei , China , South-africa , India , Chinese , Chris-turnbull-enemyinastate , Mukharjee-madivada , World-health-organization , Middle-east , Chris-turnbull , Middle-eastern

Computationally designed peptide blocks the entry of SARS-CoV, SARS-CoV-2, and MERS-CoV


Computationally designed peptide blocks the entry of SARS-CoV, SARS-CoV-2, and MERS-CoV
It is essential to face some grim facts about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen. The ongoing COVID-19 (coronavirus disease 2019) pandemic, started in December 2019, may last for many years. SARS-CoV-2, the causative agent of COVID-19, is the seventh member of the
Coronaviridae family known to infect humans.
The SARS-CoV and MERS-CoV (Middle East respiratory syndrome coronavirus), two other members of this family, are the causative agents of the recent outbreaks of the SARS and MERS epidemics. Despite the two-decades-long interaction with these viruses, there is no therapeutic solution against the SARS, COVID-19, and MERS; only supportive care.

Ramya-dwivedi , National-institute-of-technology , Research-foundation , Middle-east , National-institute , Mers-cov , Ars , Ars-cov-2 , Oronavirus , Oronavirus-disease-covid-19 , Rugs , Andemic

Researchers identify SARS-CoV-2 antiviral compounds using protein assay

During the process of SARS-CoV-2 infection, once the virus penetrates the host cell, two open reading frames, ORF1a and ORF1ab, are translated. ORF1ab is responsible for the production of 16 nonstructural proteins (nsp). Several viral proteases such as 3CLpro and PLpro (papain-like protease) produce 1-16 nsps. A new study has been published in bioRxiv* preprint server, which deals with identifying drugs that are effective as PLpro inhibitors.

Priyom-bose , World-health-organization , Drug-administration , Francis-crick-institute , Small-molecule-inhibitors , Image-credit , Middle-east , Emergency-use-authorization , High-throughput-screening , Francis-crick , Coronavirus-disease-covid-19

New polypeptide could provide universal protection against coronaviruses


New polypeptide could provide universal protection against coronaviruses
Researchers in the United States have developed an inhibitor of the spike protein found on the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that limits its formation in host human cells that would otherwise be the source of newly generated virions.
The SARS-CoV-2 virus is the agent responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic and the spike protein is the main structure the virus relies on for host cell entry.
Importantly, the inhibitor was effective against the spike proteins of other coronaviruses, including SARS-CoV-1 and Middle East respiratory syndrome CoV (MERS-CoV).

China , Houston , Texas , United-states , Wuhan , Hubei , Baylor-college-of-medicine , Jianpeng-ma , Sally-robertson , Middle-east , Baylor-college , High-potency-polypeptide-based-interference

Chimeric vaccines may provide universal protection against viruses like SARS-CoV-2

Researchers in the United States have developed “chimeric” vaccines that provided cross-protection against different strains of sarbecovirus in mice, including the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19).

Wuhan , Hubei , China , South-africa , United-states , South-african , David-martinez , Sally-robertson , Pfizer , University-of-north-carolina-at-chapel-hill , Middle-east , North-carolina