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Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.
Public Release: 1-Sep-2015 Statin side effects linked to off-target reaction in muscle mitochondria Cell Press Statin-induced myopathies are the most common side effects of these widely used cholesterol-lowering drugs, affecting millions of patients. Schirris et al. identified the Qo site of mitochondrial complex III as off-target of statin lactones and show possible mechanisms for…
Photo - of - by Joseph McClain | March 3, 2021 Pyrola media is a woodland plant, native to Europe. It produces 2-methyl-1,4-benzoquinone, a molecule that shows promise as a therapeutic, but it doesn’t produce very much of it. Dana Lashley says it’s a common phenomenon. “Often, the most interesting of these naturally occurring molecules called natural products are only produced as secondary metabolites, which means a plant could generate a really interesting-looking organic structure, but it only makes a small amount of ...