The regions and i think if you take a look at the barriers, barriers of cost, maintaining the culture and refrigeration, things we take for granted within the developed world so attributes of the nano patch, removing the culture, it's dry. that's a key advantage. but in addition to that, reducing the cost because you need a lower dose and because you don't need the needle you get around the need for trained practitioners and possibility of reduced burden in that regard, as well. >> all right. professor mark kind wl the nano patch, the inventer, we look forward to seeing this down the road and ...