Early Release - Puumala Virus Infection in Family, Switzerland - Volume 27, Number 2—February 2021 - Emerging Infectious Diseases journal
Abstract We report 3 cases of Puumala virus infection in a family in Switzerland in January 2019. Clinical manifestations of the infection ranged from mild influenza-like illness to fatal disease. This cluster illustrates the wide range of clinical manifestations of Old World hantavirus infections and the challenge of diagnosing travel-related hemorrhagic fevers. Puumala orthohantavirus (PUUV), a species of the genus Orthohantavirus within the Hantaviridae family, is an enveloped single-strand negative-sense RNA virus ( 1). The case-fatality ratio of Old World hantaviruses ranges from 1%–...