Novel macrolide–DEL-1 axis drives bone regene
<p>Scientists from Niigata University discover the ability of erythromycin to stimulate DEL-1 expression, promoting bone regeneration in aging mice. The non-antibiotic derivative EM-523, reproduces these effects. The study underscores the significance of understanding the immunomodulatory properties of macrolides for developing safe and effective clinical applications to improve bone regeneration in the elderly population.</p>
Source: eurekalert.org