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Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Research paper proposes a new method for predicting highly expressed genes based on codon usage bias and minimum free energy of mRNA secondary structures. The method involves constructing a stochastic grammar that generates sequences with high CAI and low MFE, and testing it on two mRNA vaccines. ....

Neha Mathur , Eric Topol Erictopol , Neha Mathurmay , Improves Stability , Image Credit , Codon Adaptation Index , Eric Topol , Oding Region , Covid 19 , N Vivo , Protein Expression , Ibonucleic Acid , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques

Researchers investigated the effectiveness of a circRNA vaccine against SARS-CoV-2 and its Delta and Omicron variants, which elicited significant antibody and T-cell responses in mice and rhesus macaques. ....

Jo Panuwatd Shutterstock , Image Credit , Coronavirus Disease Covid 19 , Ars Cov 2 , Oding Region , Covid 19 , Immune Response , N Vitro , Liquid Chromatography , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , T Cell ,

Evolution of the SARS-CoV-2 omicron variant

Study shows that the omicron variant shares a common ancestry with the VOI lambda and has evolved mainly because of non-synonymous mutations. ....

South Africa , World Health Organisation , Image Credit , Coronavirus Disease Covid 19 , Ars Cov 2 , Oding Region , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein ,