Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy
The pathomechanistic connection between autism and myotonic muscular dystrophy type 1.
Source: news-medical.net
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Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies
Research paper proposes a new method for predicting highly expressed genes based on codon usage bias and minimum free energy of mRNA secondary structures. The method involves constructing a stochastic grammar that generates sequences with high CAI and low MFE, and testing it on two mRNA vaccines.
Source: news-medical.net
Researchers conduct forensic analysis of SARS-CoV-2-related coronaviruses
Researchers conducted a forensic analysis of SARS-CoV-2-related coronaviruses (SARS2r-CoVs).
Source: news-medical.net
Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques
Researchers investigated the effectiveness of a circRNA vaccine against SARS-CoV-2 and its Delta and Omicron variants, which elicited significant antibody and T-cell responses in mice and rhesus macaques.
Source: news-medical.net
Evolution of the SARS-CoV-2 omicron variant
Study shows that the omicron variant shares a common ancestry with the VOI lambda and has evolved mainly because of non-synonymous mutations.
Source: news-medical.net