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A pilot study finds longer delays (more than 4 years) were associated with history of uveitis, ankylosing spondylitis at diagnosis, and being in the most vulnerable socioeconomic group.
Only patients taking peresolimab 700 mg had a significantly greater change in Disease Activity Score in 28 Joints based on the C-reactive protein level (DAS28-CRP), compared with placebo after 12 weeks.
The oral JAK inhibitor is for adults with moderately to severely active Crohn's disease whose condition failed to respond adequately or who can't tolerate one or more TNF inhibitors.
Data from a phase 2b trial showed superior symptom reduction, compared with placebo, by 1 year.
Researchers examined the therapeutic potential of ARA 3,000 BETA for treating osteoarthritis.