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Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

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