Otonomy fails phase 3, adding another twist to ear disease saga
The inner ear (Public Domain) A phase 3 clinical trial of Otonomy’s Otividex in inner ear condition Ménière's disease has missed its primary endpoint. The setback comes almost four years after the generation of mixed data from two earlier phase 3 studies persuaded Otonomy to roll the dice on another pivotal clinical trial. Investigators randomized 148 patients with Ménière's, an inner ear disease that causes symptoms including vertigo, to receive a single intratympanic injection of a sustained-release formulation of the steroid dexamethasone or placebo. The primary endpoint ass...
Source: fiercebiotech.com