Humanized mouse model for rare genetic disease developed for the first time
Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.
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Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.
Research investigates the effects of a ketogenic diet (KD) on responses to oxycodone, a commonly prescribed opioid for pain management. The study found sex-biased effects of KD on oxycodone responses in mice, suggesting potential implications for clinical pain management and treatment of opioid use disorder.
Investigators at Brigham and Women’s Hospital and collaborating institutions evaluated the dual-therapeutic effect of gene therapy in a clinically relevant model for common form of bone cancer.
Freiburg researchers discover a mechanism by which cancer cells escape the immune system.
Neuropathic pain -; abnormal hypersensitivity to stimuli -; is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV.