Early Release - Increase in Kelch 13 Polymorphisms in Plasmodium falciparum, Southern Rwanda - Volume 27, Number 1—January 2021 - Emerging Infectious Diseases journal
K13 polymorphism across Africa but is not linked to artemisinin resistance ( Our study has clear limitations. Data from only 2 healthcare facilities, with limited catchment areas, were included. Adherence to treatment was assessed by patient self-report, and drug susceptibility testing was not performed. Future research should include ring-stage susceptibility assays to contribute to understanding the role of K13 mutations in Africa. Separate testing for each drug in a combination for efficacy and continued surveillance for antimicrobial resistance are needed. Our results show that K13 muta...
Source: cdc.gov