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Harnessing power of immune system may lessen reliance on antibiotics for infections like TB

Researchers at the Francis Crick Institute have found that the body’s process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB. If this natural process can be harnessed with new treatments, it could present an alternative to, or . ....

Max Gutierrez , Enrica Pellegrino , Elliott Bernard , Beren Aylan , Pathogen Interactions In Tuberculosis Laboratory , Francis Crick Institute , Nature Microbiology , Host Pathogen Interactions , Tuberculosis Laboratory ,

How do Immune cells impact on antibiotic treatments for TB?

“By understanding more about how current antibiotics are impacted by conditions inside of cells, such as acidity, we hope it could help the search for new drugs or better drug combinations. Click to read more. ....

Pierre Santucci , Max Gutierrez , Pathogen Interactions In Tuberculosis Laboratory , Francis Crick Institute , Host Pathogen Interactions , Tuberculosis Laboratory ,

Imaging Method reveals whether Antibiotics reach Bacteria hiding in Tissues

Jan 15 2021 Read 411 Times
During bacterial infections such as tuberculosis, bacteria enter human cells posing a challenge for treatment, as antibiotics must reach and enter all infected cells in order to be effective. If researchers could select for or develop more effective antibiotics based on where they reach, this may reduce the length of treatment needed, which in turn could reduce the risk of antibiotic resistance developing.
Scientists at the Francis Crick Institute and the University of Western Australia have developed a new imaging method to see where in the infected tissues and in the cells, an antibiotic given to treat tuberculosis had reached the bacteria. The scientists are continuing to work on the method, adapting it for other types of antibiotic and to image multiple antibiotics at the same time. ....

Tony Fearns , Max Gutierrez , Pathogen Interactions In Tuberculosis Laboratory , Francis Crick Institute , University Of Western Australia , Western Australia , Host Pathogen Interactions , Tuberculosis Laboratory , டோனி பயம் , அதிகபட்சம் குட்டரெஸ் , நோய்க்கிருமி இடைவினைகள் இல் காசநோய் ஆய்வகம் , பிரான்சிஸ் கிரிக் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் மேற்கு ஆஸ்திரேலியா , மேற்கு ஆஸ்திரேலியா , தொகுப்பாளர் நோய்க்கிருமி இடைவினைகள் , காசநோய் ஆய்வகம் , நுண்ணுயிர் எதிர்ப்பிகள் , நோய்த்தொற்றுக்கு உள்ளானவர் ,