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Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2 Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus. The hormone, therefore, prevents infection of these cells by the virus and inhibits the immune response so that the virus remains in the respiratory tract for a few days, eventually leaving to find another host. The discovery by researchers at...

January 28, 2021 Melatonin encodes proteins in cells to prevent virus entry Melatonin synthesised in the lungs acts as a barrier against Covid-19 infection. This also prevents the expression of genes that are entry points for the virus, researchers at the University of São Paulo (USP) stated in a study. The study, published in the journal Melatonin Research, found that melatonin encodes proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, to prevent virus entry. The hormone, therefore, prevents infection of these cells by...

 E-Mail IMAGE: The hormone acts as a barrier against SARS-CoV-2, blocking the expression of genes that encode proteins in cells serving as viral entry points, according to a study by researchers at... view more  Credit: NIAD/NIH By Elton Alisson  |  Agência FAPESP - Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus. The hormone, therefore, prevents i...