Peptide Sample Enrichment Using µPAC™ Trapping Columns
The online preconcentration of analytes onto low volume trapping columns is a commonly used injection strategy in nano- and microbore LC-MS/MS analysis of complex peptide mixtures. Compared to direct injection onto the analytical column, a sample trapping approach provides several advantages. By effectively desalting and preconcentrating the analytes of interest onto the trap column, analytical column lifetime and workflow throughput can be improved.
Source: selectscience.net