A genetic shortcut to help visualize proteins at work
E-Mail IMAGE: A team led by Nevan Krogan at Gladstone and UCSF has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of... view more Credit: QBI, UCSF SAN FRANCISCO, CA--December 10, 2020--One of biologists' most vexing tasks is figuring out how proteins, the molecules that carry the brunt of a cell's work, do their job. Each protein has a variety of knobs, folds, and clefts on its surface that dictate what it can do. Scientists can visualize these features fairly easily on individual proteins. But p...