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New SNAP approach to customizing T cell-based immunotherapies

University of Pittsburgh researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other immunotherapies for treating cancer and other diseases. ....

Adam Butchy , Natasa Miskov Zivanov , Yaniv Tivon , Elisa Ruffo , Michael Kvorjak , Ericl Adams , Avani Parikh , Alexander Deiters , Oliveraj Finn , Emily Henderson , Jason Lohmueller , Nature Communications , Pitt Swanson School Of Engineering , University Of Pittsburgh , Hillman Cancer Center , Pitt School Of Medicine , Pitt School , Swanson School , Coeptis Therapeutics ,

Customizing T cell-based immunotherapies in a

University of Pittsburgh researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other immunotherapies for treating cancer and other diseases. The discovery could extend into solid tumors and give more patients access to the game-changing results CAR T cell therapy has produced in certain blood cancers. ....

Oliveraj Finn , Adam Butchy , Elisa Ruffo , Alexander Deiters , Jason Lohmueller , Ericl Adams , Avani Parikh , Natasa Miskov Zivanov , Michael Kvorjak , Yaniv Tivon , Method Of Research , National Institutes Of Health , Italian Foundation For Cancer Research , University Of Pittsburgh , Nature Communications , Pitt School Of Medicine , Hillman Cancer Center , Defense Advanced Research Projects Agency , Pitt Swanson School Of Engineering , Pitt School , Swanson School , Coeptis Therapeutics , National Institutes , Italian Foundation , Cancer Research , Michaelg Wells ,