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Read Time: Mitochondria are the cellâs power plants and produce the majority of a cellâs energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation. A number of different proteins in mitochondria facilitate these processes, but itâs not fully understood how these proteins are arranged inside mitochondria and the factors that can influence their arrangement. Now, scientists at the University of Copenhagen have used state-of-the-art proteomics technology to shine new light on how mitochondrial proteins gather into electron transport chain complexes, and further into so-called supercomplexes. The research, which is published in Cell Reports, also examined how this process is influenced by exercise training. ....
Mitochondria are the cell's power plants and produce the majority of a cell's energy needs through an electrochemical process called electron transport. ....
By applying mass spectrometry, scientists at the University of Copenhagen provide some of the most detailed data on how mitochondrial proteins cluster into supercomplexes - a process that makes mitochondria more efficient at producing energy. The findings, which were published in Cell Reports, is a precious resource for the scientific community, especially those tackling mitochondrial adaptations to exercise training or mitochondrial diseases. ....