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Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation.

United statesEmily hendersonHiroyoshi fujiokaYasuyuki ozekiJournal of the american chemical societyTokyo institute of technologyUniversity of tokyoTokyo institute of technology techTokyo techProfessor mako kamiyaAssistant professor hiroyoshi fujiokaTokyo instituteAmerican chemicalMako kamiyaNex vivoFluorescence imaging

Sensitive Raman Probe Detects Enzyme Expression in Tissues

Sensitive Raman Probe Detects Enzyme Expression in Tissues
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United statesYasuyuki ozekiHiroyoshi fujiokaTokyo institute of technology techJournal of the american chemical societyUniversity of tokyoTokyo techProfessor mako kamiyaAssistant professor hiroyoshi fujiokaTokyo instituteAmerican chemical

Raman Probe Detects Enzyme Expression in Heterogeneous Tissues

Raman Probe Detects Enzyme Expression in Heterogeneous Tissues
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United statesYasuteru uranoHiroyoshi fujiokaYoshihiro misawaAyumi komazawaRyosuke kojimaTakaha mizuguchiMinoru kawataniSpencer john sprattFumiaki obataYasuyuki ozekiInternational research frontiers initiativeSchool of biostudiesTokyo institute of technologyUniversity of tokyoDepartment of electrical engineering

Highly sensitive Raman probe detects enzyme e

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation. The strategy allows a synthesis of highly activatable Raman probes with high aggregation and multiplexing ability, making it a promising tool for extending the range of Raman probes for the detection of multiple enzyme activities in heterogeneous biological tissues.

United statesYasuyuki ozekiHiroyoshi fujiokaJournal of the american chemical societyTokyo institute of technologyUniversity of tokyoTokyo institute of technology techMethod of researchTokyo techProfessor mako kamiyaAssistant professor hiroyoshi fujiokaTokyo instituteAmerican chemicalSelective ex vivo