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Why cells don't get stuck - generalised cell migration and motility modelled mathematically


Why cells don t get stuck -.
22 Jan 2021
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Cell movement has now been mathematically modelled by an interdisciplinary team of theoretical and experimental physicists. Understanding this fundamental process will allow scientists to predict cell behaviours and improve targeted treatment development. Unlike previous, more specific models, this new approach provides a tool to understand a broad spectrum of biological observations.
Image: Cancer cells moving on glycoproteine strips: These strips act like splints, which allow to control and to study the movement of the cells better. 
Credit: Rädler Lab, Ludwig Maximilians Universität München
Cell velocity, or how fast a cell moves, is known to depend on how sticky the surface is beneath it, but the precise mechanisms of this relationship have remained elusive for decades. Now, researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) and Ludwig Maximilians Un ....

Max-delbr , Ludwig-maximilians-universit , Behnam-amiri , Martin-falcke , Proceedings-of-the-national-academy-sciences , Mathematical-cell-physiology-lab , Helmholtz-association , Molecular-medicine , National-academy , Professor-martin-falcke , Cell-physiology-lab , கணித-செல்-உடலியல்-ஆய்வகம்

Mathematical Model Captures Relationship between Speed and Surface in Cell Movement


Mathematical Model Captures Relationship between Speed and Surface in Cell Movement
Cancer cells vis - 3d rendered image, enhanced scanning electron micrograph (SEM) of cancer cell. Visual of overall shape of the cell s surface at a very high magnification. Medical research concept.
January 21, 2021
Just as how fast your car moves depends on how well your wheels grip the road, the speed at which a cell moves depends on how well it attaches to the surface it moves on. Deciphering the specific mechanics of the complex interplay between surface and speed in cell movement can lead to a better understanding of basic biological processes, such as how cells move during development to form a full-sized organism, as well as pathological processes, such as how cancer cells radiate from an origin to metastasize. ....

Max-delbr , Ludwig-maximilians-universit , Behnam-amiri , Martin-falcke , Proceedings-of-the-national-academy-sciences , Mathematical-cell-physiology-lab , Helmholtz-association , Molecular-medicine , National-academy , Professor-martin-falcke , Cell-physiology-lab , கணித-செல்-உடலியல்-ஆய்வகம்

Researchers figure out the precise mechanics involved in cell motility


Researchers figure out the precise mechanics involved in cell motility
Theoretical physicists from Berlin teamed up with experimental physicists from Munich to determine the precise mechanics involved in cell motility. The findings were published in the journal Proceedings of the National Academy of Sciences (PNAS).
Cell velocity, or how fast a cell moves, is known to depend on how sticky the surface is beneath it, but the precise mechanisms of this relationship have remained elusive for decades. Now, researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) and Ludwig Maximilians Universität München (LMU) have figured out the precise mechanics and developed a mathematical model capturing the forces involved in cell movement. The findings, reported in the journal ....

Munich , Bayern , Germany , Berlin , Max-delbr , Ludwig-maximilians-universit , Behnam-amiri , Martin-falcke , Emily-henderson , Proceedings-of-the-national-academy-sciences , Mathematical-cell-physiology-lab , Helmholtz-association

How cells move and don't get stuck

Theoretical physicists from Berlin teamed up with experimental physicists from Munich to determine the precise mechanics involved in cell motility. The findings were published in the journal ....

Max-delbr , Ludwig-maximilians-universit , Behnam-amiri , Martin-falcke , Proceedings-of-the-national-academy-sciences , Mathematical-cell-physiology-lab , Helmholtz-association , Molecular-medicine , National-academy , Professor-martin-falcke , Cell-physiology-lab , Biology