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Patients treated with indomethacin had a reduction in the number of days to become fever-free, and reduction in cough and muscle pain by half compared to the paracetamol set.
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Patients treated with indomethacin had a reduction in the number of days to become fever-free, and reduction in cough and muscle pain by half compared to the paracetamol set.
A pre-print published recently in
Medrxiv has advanced the case to use indomethacin, a drug conventionally used in the treatment of rheumatoid arthritis, for faster symptomatic relief and preventing progression of pneumonia in COVID-19 patients.
A total of 104 patients who had tested COVID-19 positive received the drug, along with standard care in two centres — Narayana Medical College, Nellore, Andhra Pradesh, and Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra. The study was conceived by Rajan Ravichandran, senior nephrologist, MIOT Hospital, here, and executed along with R. Krishnakumar of the Department of Engineering Design at the Indian Institute of Technology-Madras, besides researchers from the participating hospitals. The authors have called for indomethacin to replace paracetamol if there is no contraindication for its use.

Wardha , Maharashtra , India , Madras , Tamil-nadu , Nellore , Andhra-pradesh , Rajan-ravichandran , Datta-meghe-institute-of-medical-sciences , Department-of-engineering-design , Narayana-medical-college , Indian-institute-of-technology