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A Beginner's Guide to Creating and Using Packages in Python

A Beginner's Guide to Creating and Using Packages in Python
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Between Packages , Add Modules , Add Sub Packages , Work With , Distribute Your Package , Package Index , Install Package Management , Python Package , Python Package Index ,

How to Install Python in Ubuntu [3.12]

How to Install Python in Ubuntu [3.12]
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Scootersthe Turboant , Python Is Installed , Install Python , Python Using , Advanced Package Tool , Personal Package Archives , Ubuntu From , Python Package , Installing Python , Latest Version , Advanced Package , Ubuntu Is Easy ,

Frontiers | Crystal structures of glycoprotein D of equine alphaherpesviruses reveal potential binding sites to the entry receptor MHC-I

Cell entry of most alphaherpesviruses is mediated by the binding of glycoprotein D (gD) to different cell surface receptors. Equine herpesvirus type 1 (EHV-1) and EHV-4 gDs interact with equine major histocompatibility complex I (MHC-I) to initiate entry into equine cells. We have characterized the gD-MHC-I interaction by solving the crystal structures of EHV-1 and EHV-4 gDs (gD1, gD4), performing protein-protein docking simulations, surface plasmon resonance (SPR) analysis, and biological assays. The structures of gD1 and gD4 revealed the existence of a common V-set immunoglobulin-like (IgV-like) core comparable to those of other gD homologs. Molecular modeling yielded plausible binding hypotheses and identified key residues (F213 and D261) that are important for virus binding. Altering the key residues resulted in impaired virus growth in cells, which highlights the important role of these residues in the gD-MHC-I interaction. Taken together, our results add to our understanding of t ....

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Django 4.2 released

Django 4.2 released
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Mariusz Felisiak , Python Package , Open Source ,