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Necrostatin-1 counteracts aluminum's neurotoxic effects – Engineering Evil


 
New studies in mice support toxic role of aluminum in neurodegenerative conditions, according to report in Restorative Neurology and Neuroscience
Amsterdam, NL, August 2, 2013 – Investigators have linked aluminum accumulation in the brain as a possible contributing factor to neurodegenerative disorders such as Alzheimer’s disease. A new study published in
Restorative Neurology and Neuroscience sheds light on the mechanism underlying aluminum-induced neuronal cell death and identifies necrostatin-1 as a substance which counteracts several of aluminum’s neurotoxic effects.
Researchers have long focused on why neurons die in degenerative diseases. One process is apoptosis, a form of gene-directed programmed cell death which removes unnecessary, aged, or damaged cells. When neurons die as a result of stroke, trauma, or other insult, the process is known as necrosis. Recently, a new type of necrosis, necroptosis (programmed necrosis), has been implicated in th ....

Noord Holland , Daphne Watrin , Ralph Turchiano , Qiao Niu , Qinli Zhang , Department Of Occupational Health , Shanxi Medical University , Ministry Of Education Key Laboratory , Institute Of Preventive Medicine , Restorative Neurology , Occupational Health , Education Key Laboratory , Public Health , Preventive Medicine , Morris Water Maze , நூற்த் ஹாலண்ட் , துறை ஆஃப் தொழில் ஆரோக்கியம் , அமைச்சகம் ஆஃப் கல்வி விசை ஆய்வகம் , நிறுவனம் ஆஃப் ப்ரெவெஂடிவ் மருந்து , மறுசீரமைப்பு நரம்பியல் , தொழில் ஆரோக்கியம் , கல்வி விசை ஆய்வகம் , பொது ஆரோக்கியம் , ப்ரெவெஂடிவ் மருந்து , மோரிஸ் தண்ணீர் பிரமை ,