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CNN CNN Newsroom November 28, 2021 18:10:00

What makes you say that as many folks say they re still gathering evidence and information? good afternoon, paula. thank you for voog me. i think, first of all, a shout-out to the whole covid community around the world that s been able to sequential this variant and provide amazing information to the world so quickly. it s an amazing feat. what they show is this is a virus now with at least 50 mutations, many of them spanning previous areas of concern. at least 30 mutations in the protein alone we know lead to immune evasion and escape and also increase replication. this, paula, is what makes it so concerning to us. what we hear again and again from health experts over the past 48 hours is we don t know too much about this variant but people should get a vaccine or a booster if they ve already had their first two shots. here you re saying it s ....

Paula Reid In Washington , Shout Out , Covid Community , Voog Me , Omicron Variant , Health Experts ,

"Single-molecule studies of helicases and translocases in prokaryotic g" by Kelsey S. Whinn, Antoine M. van Oijen et al.

Helicases involved in genomic maintenance are a class of nucleic-acid dependent ATPases that convert the energy of ATP hydrolysis into physical work to execute irreversible steps in DNA replication, repair, and recombination. Prokaryotic helicases provide simple models to understand broadly conserved molecular mechanisms involved in manipulating nucleic acids during genome maintenance. Our understanding of the catalytic properties, mechanisms of regulation, and roles of prokaryotic helicases in DNA metabolism has been assembled through a combination of genetic, biochemical, and structural methods, further refined by single-molecule approaches. Together, these investigations have constructed a framework for understanding the mechanisms that maintain genomic integrity in cells. This review discusses recent single-molecule insights into molecular mechanisms of prokaryotic helicases and translocases. ....

Single Molecule ,

CNN CNN Newsroom With Poppy Harlow and Jim Sciutto November 5, 2021 13:20:00

May be actually useful thing to do. but at the data we have with the clinical trials, enrolling people that have high risk of progression. i would say, though, the two drugs, the merck drug and the pfizer drug are different in their mechanism of action and the pfizer drug is something called protease inhibitor. it inhibits a step in the viral replication in which an enzyme, protease, cuts down the virus. when you make cookies, you make cookies and you try to cut them, so you have the final shape, this drugs are very similar to drugs we use for the treatment of hiv, so a lot of the research in advancing hiv research led to drugs for the treatment of covid. okay, so, everybody loves a pill. it solves a problem. it is easy, pop it, everything is good. just to be clear here, you re saying folks should still get vaccinated to prevent getting to this point, right? less likely you are infected even in the first place, just i want to make that clear ....

Merck Drug , Protease Inhibitor , Antiviral Pill , Hiv Research , Covid 19 , Pop It ,

BBCNEWS BBC News October 29, 2021 16:19:00

The rate of replication of this virus is above one, in other words, it is on an upward trend. it would be wrong to immediately think that just because over half term things go down of that that it s time that we all relaxed and threw away all precaution and just started to infect each other. 0ver precaution and just started to infect each other. over a million people in fact dead in this country, and, you know, and every day we are seeing another thousand or so going to hospital. 1,000 deaths in the past seven days. i mean, these are astonishingly high numbers. this is not what we expect with a flu season at all. this is a very nasty virus, and we really do need to get it under control so that we can go into the winter season knowing that the rates are low enough. haifa the winter season knowing that the rates are low enough. the winter season knowing that the rates are low enough. how much more dancerous rates are low enough. how much more dangerous is rates are low enough. how muc ....

Each Other , 0ver Precaution , A Million , Flu Season , Dancerous Rates , Winter Season Rates ,